
Chicken Bubble Biscuit Bake Casserole
If you’re looking for a quick, easy, and incredibly satisfying meal to please the whole family, then the Chicken Bubble Biscuit Bake Casserole is the answer. This delightful dish combines tender chicken, fluffy biscuits, and a creamy sauce that brings everything together in one harmonious, comforting bake. Let’s dive into why this casserole is a go-to choice for busy weeknights and special gatherings alike.
Why You’ll Love This Casserole
This casserole is more than just a meal; it’s an experience. Here’s why you’ll love it:
- Simplicity: With minimal prep time and easy-to-find ingredients, this dish is a breeze to make.
- Flavor Fusion: The combination of chicken, herbs, and creamy sauce creates a taste that’s hard to resist.
- One-Pan Wonder: Everything cooks in one casserole dish, making cleanup a snap – perfect for busy families.
Ingredients
- 2 cups cooked chicken, shredded or diced
- 1 can (10.5 oz) cream of chicken soup
- 1/2 cup milk
- 1/2 cup sour cream
- 1 teaspoon garlic powder
- 1 teaspoon onion powder
- Salt and pepper to taste
- 1 can (16.3 oz) refrigerated biscuits
- 1 cup shredded cheddar cheese
- 1/4 cup chopped green onions (optional)

Directions
- Preheat the Oven: Start by preheating your oven to 350°F (175°C).
- Prepare the Chicken Mixture: In a large mixing bowl, combine the cooked chicken, cream of chicken soup, milk, sour cream, garlic powder, onion powder, salt, and pepper. Mix well until all ingredients are fully incorporated.
- Layer the Mixture: Pour the chicken mixture into a greased 9×13 inch casserole dish, spreading it evenly out.
- Prepare the Biscuits: Open the tube of refrigerated biscuits and cut each one into quarters. You can do this easily by using kitchen scissors.
- Add the Biscuits: Scatter the biscuit pieces evenly over the top of the chicken mixture. Don’t worry if some chicken is still exposed – that’s okay.
- Cheese It Up: Sprinkle the shredded cheddar cheese over the biscuit pieces. If you’re a cheese lover, feel free to add extra!
- Bake the Casserole: Place the casserole in the preheated oven and bake for 25-30 minutes, or until the biscuits are golden brown and cooked through.
- Finishing Touches: Once baked, remove from the oven and let it cool for about 5 minutes before serving. For a fresh touch, sprinkle chopped green onions on top right before serving.
Tips for Success
- Use Leftover Chicken: This casserole is a fantastic way to use up leftover chicken from a previous meal, saving you both time and effort.
- Substitutions: Feel free to swap the chicken for turkey or rotisserie chicken if you’re short on time.
- Make It Healthy: You can use low-fat sour cream and cheese to lighten the dish without sacrificing much flavor.
Storage and Reheating
If you happen to have leftovers (which is likely because it’s so good), store them in an airtight container in the refrigerator for up to three days. Reheat in the microwave for an individual serving or place it back in the oven covered with foil until heated through.
Conclusion
The Chicken Bubble Biscuit Bake Casserole is the perfect recipe for ensuring that everyone at the table leaves satisfied. It’s comforting, straightforward, and versatile enough to cater to various tastes and dietary preferences. Enjoy this culinary delight tonight and make mealtime a memorable occasion

Chicken Bubble Biscuit Bake Casserole
Ingredients
For the chicken mixture
- 2 cups cooked chicken, shredded or diced Use leftover chicken if available.
- 1 can cream of chicken soup (10.5 oz)
- 1/2 cup milk
- 1/2 cup sour cream Can use low-fat option.
- 1 teaspoon garlic powder
- 1 teaspoon onion powder
- to taste salt and pepper
For the casserole
- 1 can refrigerated biscuits (16.3 oz) Cut each biscuit into quarters.
- 1 cup shredded cheddar cheese Feel free to add more if desired.
- 1/4 cup chopped green onions (optional) For garnish before serving.
Instructions
Preparation
- Preheat your oven to 350°F (175°C).
- In a large mixing bowl, combine cooked chicken, cream of chicken soup, milk, sour cream, garlic powder, onion powder, salt, and pepper. Mix well.
- Pour the chicken mixture into a greased 9x13 inch casserole dish, spreading it evenly.
- Open the tube of refrigerated biscuits and cut each one into quarters.
- Scatter the biscuit pieces evenly over the top of the chicken mixture.
- Sprinkle the shredded cheddar cheese over the biscuit pieces.
Baking
- Place the casserole in the preheated oven and bake for 25-30 minutes, until the biscuits are golden brown.
- Remove from oven and let cool for about 5 minutes. Garnish with chopped green onions before serving.